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MDGL

Madrigal Pharmaceuticals, Inc.

MDGL

NASDAQ·Healthcare·Biotechnology·Mkt cap $11.9B

$522.26

+1.53%

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Our plain-language verdict, the thesis, risk factors, and what is changing about the business.

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52-Week Range

$284.02 - $615.00

P/E

-40.80

Fwd P/E

523.49

Beta

-1.06

Div Yield

0.00%

Avg Vol

328.7K

Shares Out

22.9M

Mkt Cap

$11.9B

Price action

Price chart

Up 71.4% over the trailing year

1W
1M
3M
6M
YTD
1Y
5Y
MAX

Total returns

Price performance

Total return across standard periods - splits & dividends adjusted by FMP. Periods longer than 1Y show annualized in the tooltip.

Why we rate it this way

The thesis at a glance

Bull and bear case · plain-English context across the five lenses we evaluate.

Bull Case

4 reasons

  • Liver-directed selective mechanism of action minimizing systemic thyroid hormone effects
  • Strategic partnership with Hoffmann-La Roche providing development and commercialization support
  • Advanced clinical stage (Phase III) with lead candidate addressing large unmet NASH market need
  • Focused pipeline strategy reducing development complexity and capital requirements

Bear Case

2 risks

  • Low volatility (beta -1.1).
  • Growth premium of 21.6x vs Biotech & Therapeutics peers. Significant premium - requires sustained high growth to justify.

Growth

Turning profitable

Phase III clinical trial success for resmetirom in NASH treatment

Value

Growth premium of 21.6x vs Biotech & Therapeutics peers. Significant premium - requires sustained high growth to justify.

Momentum

Weak

-5.9% over 3m

Quality

Excellent

High-growth business (257% revenue growth, 93% gross margin). Pre-profit but investing in growth.

Dividend

None

No dividend

Earnings track record

Latest print - beat on both lines

AI-summarized recap of last quarter, plus the surprise on every print.

Next: Apr 29, 2026

Q2 26 RECAP

MAY 6, 2026

Reported EPS of -$3.25 vs -$3.61 consensus (+10.0% surprise). Revenue of $311.3M vs $301.1M expected (+3.4%). Beat on both top and bottom lines.

EPS beat +10.0%
Rev beat +3.4%
Double beat

EPS surprise · last 4Q

1 of 1 beats

Q2 26

+10.0%

Next: Apr 29, 2026

Revenue trend · last 8Q

+1354%

+362%

+211%

+127%

Q2 24

Q3 24

Q4 24

Q1 25

Q2 25

Q3 25

Q4 25

Q1 26

$14.6M

$62.2M

$103.3M

$137.3M

$212.8M

$287.3M

$321.1M

$311.3M

Margins · last 8Q

Gross

Operating

Profit

-30.3%

Wall Street consensus

7 analysts · 86% Buy

Live ratings and price targets aggregated across covering analysts.

Buy

6

86%

Hold

1

14%

Sell

0%

Median Price Target

$649.00

+24.3% vs $522.26

Low $578.00
Median $649.00
High $709.00

Latest: Piper Sandler · Jun 24, 2026

3 analysts covering

vs Industry

How MDGL stacks vs Biotechnology

Stock metrics vs industry averages. Green = better than industry.

Industry comparison data unavailable for this stock.