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SION

Sionna Therapeutics, Inc.

SION

NASDAQ·Healthcare·Biotechnology·Mkt cap $330.0M

$6.75

-7.66%

P/E

-3.10

Mkt Cap

$330.0M

52-Wk Range

$4.01–$54.97

52-Week Range

$4.01 - $54.97

P/E

-3.10

Fwd P/E

-2.67

Beta

1.32

Div Yield

0.00%

Avg Vol

1.4M

Shares Out

45.0M

Mkt Cap

$330.0M

Price action

Price chart

Down 70.2% over the trailing year

Total returns

Price performance

Total return across standard periods - splits & dividends adjusted by FMP. Periods longer than 1Y show annualized in the tooltip.

Why we rate it this way

The thesis at a glance

Bull and bear case · plain-English context across the five lenses we evaluate.

Bull Case

3 reasons

  • Specialized focus on CFTR function normalization with differentiated mechanisms
  • Access to proprietary research and development capabilities in rare genetic diseases
  • Potential to address patient populations with limited or no current treatment options

Bear Case

1 risk

  • Average volatility.

Growth

Stable outlook

Expansion of cystic fibrosis treatment options and market penetration

Value

Deep value opportunity - significant discount to Biotech & Therapeutics peers

Momentum

Falling

-80.1% over 3m

Quality

Loss-making

Below average quality

Dividend

None

No dividend

Earnings track record

Recent earnings results

AI-summarized recap of last quarter, plus the surprise on every print.

Next: Nov 4, 2026

Q3 26 RECAP

AUG 6, 2026

Reported EPS of -$0.66 vs -$0.65 consensus (-1.5% surprise).

EPS miss

EPS surprise · last 4Q

0 of 1 beats

Estimate

Actual

Q3 26

-1.5%

Revenue trend · last 8Q

Q3 24

Q4 24

Q1 25

Q2 25

Q3 25

Q4 25

Q1 26

Q2 26

$0

$0

$0

$0

$0

$0

$0

$0

Margins · last 8Q

No margin history available.

Wall Street consensus

10 analysts · 30% Buy

Live ratings and price targets aggregated across covering analysts.

Buy

3

30%

Hold

7

70%

Sell

0%

Median Price Target

Latest: Citi · Aug 10, 2026

vs Industry

How SION stacks vs Biotechnology

Stock metrics vs industry averages. Green = better than industry.

Industry comparison data unavailable for this stock.